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For informational purposes only. Consult your local medical authority for advice.

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Before using dutasteride/ tamsulosin:

Some medical conditions may interact with dutasteride/tamsulosin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines or other substances
  • if you have heart failure, kidney problems, urinary tract problems, or problems urinating
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any sulfonamide (sulfa) medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), probenecid, sulfamethoxazole, sulfonylureas (eg, glyburide), valdecoxib, or zonisamide
  • if you will be having a certain type of eye surgery (cataract surgery)
  • if you have a history of high or low blood pressure, prostate cancer, increased serum prostate-specific antigen (PSA) levels, abnormal liver function tests, or liver problems
  • if you take medicine for high blood pressure

Some MEDICINES MAY INTERACT with dutasteride/tamsulosin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Azole antifungals (eg, fluconazole, itraconazole, ketoconazole, posaconazole), cimetidine, fluoxetine, HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, clarithromycin, erythromycin), nefazodone, paroxetine, telithromycin, or terbinafine because they may increase the risk of dutasteride/tamsulosin's side effects
  • Phosphodiesterase type 5 (PDE5) inhibitors (eg, sildenafil) or other medicines that contain alpha-blockers (eg, prazosin) because symptoms of low blood pressure (eg, severe dizziness, light-headedness, fainting) may occur
  • Warfarin because the risk of side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if dutasteride/tamsulosin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

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